Meiosis in autotriploid Physalis pubescens L.

New withanolides with TRAIL-sensitizing effect from Physalis pubescens L.

Physalis pubescens L. plant produces nutritious and healthy fruits, called husk tomato or hairy ground cherry. However, its bioactive components are largely unknown. Four new withanolide steroids (1-4) together with one known withanolide (5) were isolated from the extract of P. pubescens L. and their chemical structures were established by extensive spectroscopic analyses. Compounds 1, 3 and 5 ...

A Possible Inhibitory Effect of Physalis (Physalis pubescens L.) On Diabetes in Male Rats

The present study was designed to investigate the possible antidiabetic, hypolipidaemic and antioxidant effects of physalis. Diabetes was induced in Albino rats by administration of alloxan monohydrate (150 mg/kg, body weight i.p). Physalis was administered at a single 1 ml dose per day to these diabetic rats for 21 days. The effect of physalis on blood glucose, serum insulin and pancreatic ins...

Physalis Angulata L . : an Ethanopharmacological Review

Fruit abscission by Physalis species as defense against frugivory

Fruit abscission as a response to herbivory is well-documented in many plant species, but its effect on further damage by mobile herbivores that survive fruit abscission is relatively unstudied. Physalis plants (Solanaceae) abscise fruit containing feeding larvae of their main frugivore, Heliothis subflexa Guenée (Lepidoptera: Noctuidae), a specialist moth. We tested the ability of H. subflexa ...

A natural inhibitor of kidney-type glutaminase: a withanolide from Physalis pubescens with potent anti-tumor activity

Kidney-type glutaminase (KGA), a mitochondrial enzyme converting glutamine to glutamate for energy supply, was over-expressed in many cancers and had been regarded as a promising therapeutic target in recent years. Structure-based virtual ligand screening predicted physapubescin K, a new withanolide from Physalis pubescens, to be potential KGA inhibitor. Enzyme activity inhibition assays and mi...